原发性肝癌合并门静脉癌栓的放射治疗进展

原发性肝癌合并门静脉癌栓的发病率相当高，治疗效果差、生存期短、合并症多，一直是肝癌研究领域中重要且难度高的课题。近年来放射治疗运用于原发性肝癌合并门静脉癌栓的报道越来越多，包括三维适形放疗、立体定向放疗、质子放疗、同位素内放疗以放疗为主的综合治疗等，主要根据患者的病情及癌栓情况合理制定治疗措施，进行个体化和序贯性的治疗。本文就放射治疗原发性肝癌合并门静脉癌栓的相关研究进展作一综述。

The progress of radiation therapy for primary liver cancer with portal vein tumor thrombus

The incidence of primary liver cancer with portal vein tumor thrombus （PVTT） is very high. It is an important and difficult problem in the research field of liver cancer because of poor therapeutic effect, short lifetime and more complications. The radi- ation treatments for primary liver cancer with PVTF were reported more and more frequently,including three dimensional conformal radi- ation therapy, stereotactic body radiation therapy,proton radiation therapy,internal isotope therapy, radiation therapy combined with oth- er therapeutic approach, etc. The therapeutic approach should be individualized and sequential according to the patients＇ condition and the type of PVTT. This article reviews the recent literature and the relevant issues concerning the radiation treatments for primary liver cancer with PVTF.