Immunization with recombinant surface antigen P50 of Babesia gibsoni expressed in insect cells induced parasite growth inhibition in dogs |
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| Authors: | Fukumoto Shinya Tamaki Yoh Shirafuji Hiroaki Harakawa Shinji Suzuki Hiroshi Xuan Xuenan |
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| Affiliation: | National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan. |
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| Abstract: | This is a report of a vaccine trial directed against Babesia gibsoni infection in dogs with the use of the recombinant antigen P50. Dogs immunized with P50 showed partial protection manifested as a significantly low level of parasitemia. The results indicated that P50 is a primary vaccine candidate molecule against canine B. gibsoni infection. |
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