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Evaluation of diagnostic assays for hepatitis E virus in outbreak settings |
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| Authors: | Myint Khin Saw Aye Endy Timothy P Gibbons Robert V Laras Kanti Mammen Mammen P Sedyaningsih Endang R Seriwatana Jitvimol Glass Jonathan S Narupiti Sumitda Corwin Andrew L |
| Affiliation: | Department of Virology, USAMC-AFRIMS, 315/6 Rajvithi Road, Bangkok 1040, Thailand. myintk@afrims.org |
| Abstract: | Hepatitis E virus (HEV) is a major cause of hepatitis. We evaluated five HEV antibody diagnostic assays by using outbreak specimens. The Abbott immunoglobulin G (IgG), Genelabs IgG, and Walter Reed Army Institute of Research (WRAIR) IgM assays were about 90% sensitive; the Abbott IgG and WRAIR total Ig and IgM assays were more than 90% specific. |
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