耐甲氧西林金黄色葡萄球菌引起老年人呼吸道感染的探讨

目的了解老年人呼吸道感染耐甲氧西林金黄色葡萄球菌(MRSA)的分离率及耐药情况。方法对我院60岁以上的老年患者痰标本分离出的金黄色葡萄球菌进行MRSA的鉴定,并对其发生率及耐药性展开讨论。结果老年患者痰标本分离出的金黄色葡萄球菌178株,其中MRSA检出164株,检出率为90.2%。MRSA对多种抗生素的耐药率均在以上,对复方新诺明和四环素的耐药率均为24%,对万古霉素100%敏感。结论老年人呼吸道感染金黄色葡萄球菌的发生率较高,尤其MRSA检出率极高。结合老年患者的临床特点,并根据流行病学调查及药物敏感试验数据合理应用抗生素,可有效控制MRSA的暴发流行。

Investigation on Respiratory Infection Induced by Methicillin-resistant Staphylococcus Aureus in Elderly

Objective To understand isolating rate and drug resistance in elderly respiratory infection of methicillin-resistant Staphylococcus aureus（MRSA）.Methods To make identification of MRSA which isolated from sputum samples of 60 years or older patients,and to disscuss the incidence rate and its drug resistance.Results 178 strains of staphylococcus aureus were isolated from sputum samples of elderly patients,including MRSA 164 strains,the detection rate was 90.2%.MRSA has resistant to many antibiotics.The resistance rates of cotrimoxazole and tetracycline were all 24%,and 100% sensitive to vancomycin.Conclusion Staphylococcus aureus infection has higher incidence in the elderly respiratory.In particular,MRSA has very high detection rate.Using the clinical characteristics of the aged,according to epidemiological investigation and drug sensitivity test data,to reasonable use antibiotics and effective control MRSA outbreaks.