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帕夫林治疗轻型口疮的疗效观察
引用本文:苏葵,胥红,吴纪楠. 帕夫林治疗轻型口疮的疗效观察[J]. 广东牙病防治, 2006, 14(1): 41-42
作者姓名:苏葵  胥红  吴纪楠
作者单位:1. 中山市人民医院口腔科,广东,中山,528403
2. 广东省中山市博爱医院口腔科
摘    要:目的探讨帕夫林治疗轻型复发性口疮的临床效果和药效机理。方法183例轻型复发性口疮患者分为两组,分别口服帕夫林胶囊、多抗甲素片治疗,观察其治疗效果,并于治疗前、后采用流式细胞术检测患者外周血T淋巴细胞亚群。结果帕夫林治疗组总有效率达80.43%,治疗后CD3'、CD4' CO4/CO8升高,CDg降低,与治疗前比较差异有统计学意义;帕夫林疗效优于多抗甲素。结论采用帕夫林胶囊治疗轻型复发性口疮效果肯定,其机理可能为提高了患者的细胞免疫功能。

关 键 词:复发性口疮  免疫调节剂  T细胞亚群  流式细胞术

The Clinical Study of the Effect of Total Glucosides of Paeony Capsules on Recurrent Aphtha Ulceration
SU Kui,XU Hong,WU Ji'nan. The Clinical Study of the Effect of Total Glucosides of Paeony Capsules on Recurrent Aphtha Ulceration[J]. Journal of Dental Prevention and Treatment, 2006, 14(1): 41-42
Authors:SU Kui  XU Hong  WU Ji'nan
Abstract:Objective To evaluate the effect of total glucosides of paeony capsules on treatment of mild type recurrent aphtha ulceration(RAU).Methods 183 patients were divided into 2 groups and treated by total glucosides of paeony capsules or polyactin A respectively and the clinical effect was observed.The ratio of T lymphocyte subgroups was examined with flow cytometry.Results In the total glucosides of paeony capsules treated group,the effect rate was 80.43% and the ratio of patients' CD_3,CD_4,CD_4/CD_8 increased while the ratio of CD_8 decreased remarkably.Conclusion The total glucosides of paeony capsules is effective for mild type RAU through regulating the patient's cell immunity function.
Keywords:Recurrent aphtha ulceration Immunity regulator T lymphocyte subgroup Flow cytometry
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