Direct immunofluorescence in lesional and uninvolved skin in dle |
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Authors: | Sandra A Srinivas C R Balachandran C Shenoi S D |
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Affiliation: | department of Dermatology, Kasturba Medical College, Manipal- 576119, Karnataka, India, . |
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Abstract: | Direct immunofluroscence was evaluated in 16 patients with DLE including 1 case of lupus profundus and 4 with disseminated DLE. A BMZ band with multiple immunoreactants was demonstrated in lesional skin in 14 patients (87.5%), while 2 had only single immunoreactants. C3 and lgM were the commonest reactants followed by lgG, lgA and fibrinogen. A perifollicular prominence was seen in several patients. Four patients showed a band in uninvolved skin. This may indicate a potential to develop SLE. ANA was also positive in 5 patients but ds DNS was negative. |
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