两头毛的的化学成分和药理作用研究进展

两头毛Incarvillea arguta(Royle)Rovle为紫威科角蒿属植物,主产于西南地区,为各民族常用中草药。两头毛含有多种化学成分,目前从其根茎或者地上部分分离得到单萜、环烯醚萜、倍半萜、三萜、甾体、生物碱、黄酮、酰胺、苯丙素等。两头毛提取物或所含化学成分具有促细胞分化、抗炎、抗菌、抗氧化、防治胆石症等作用,临床用于治疗肝炎、结石病等,疗效显著。综述了2008—2013年两头毛的化学成分和药理作用,为其开发利用提供参考。

Research progress on the chemical constituents and pharmacological activities of Incarvillea arguta

Incarvillea arguta (Royle) Rovle, the plant of Bignoniaceae Incarvillea Juss., is distributed in southwest area in China as a folk medicine used by several nationalities. The main chemical constituents separated from I. arguta are monoterpenoids, iridoids, sesquiterpenoids, triterpennoids, sterides, alkaloids, flavonoids, amides and phenylpropanoids. Modern pharmacological studies have demonstrated that I. arguta performs promoting the activities of cell differentiation, anti-inflammation, antibacterial, anti-oxidation, and preventing gallstone and I. arguta is widely used in the treatment of hepatitis and lithiasis. The recent research progress from 2008 to 2013 on the chemical constituents and pharmacological activities of I. arguta are reviewed in this paper, which could provide references for the further utilization of the plant.