川乌氯仿部位的化学成分研究

目的研究川乌氯仿部位的化学成分。方法通过硅胶、碱性氧化铝柱色谱进行分离纯化,并根据理化性质和波谱数据鉴定化合物的结构。结果分离得到9个化合物,分别鉴定为次乌头碱(1)、金色酰胺醇酯(2)、乌头碱(3)、松胞素B2(4)、宋果灵(5)、新乌头碱(6)、多根乌头碱(7)、北乌碱(8)、附子灵(9)。结论化合物2为首次从乌头属植物中分离得到,化合物4为首次从植物界中分离得到。

Chemical constituents in chloroform fraction from parent roots of Aconitum carmichaeli

Abstract: Objective To study the chemical constituents in chloroform fraction from the parent root of Aconitum carmichaeli. Methods The compounds were isolated by column chromatography (silica gel and alkaline alumina). Their structures were identified on the basis of physicochemical properties and spectroscopic data. Results Nine compounds were separated and identified as hypaconitine (1), aurantiamide acetate (2), aconitine (3), cytochalasin B2 (4), songorine (5), mesaconitine (6), karacoline (7), beiwutine (8), and fuziline (9). Conclusion Compound 2 is obtained from plants of Aconitum L. for the first time and compound 4 is isolated from plants for the first time.