普通球囊与切割球囊成形术对冠状动脉支架内再狭窄的近远期疗效

目的　对切割球囊成形术 (CBA)与普通球囊成形术 (POBA)支架内再狭窄病变的近远期血管造影结果比较 ,评价 CBA对支架内再狭窄病变的有效性。方法　 37例 ,共 39处病变 ,2 3处进入 CBA组 ,16处进入 POBA组。分别比较术后即刻及远期定量冠状动脉造影最小血管径 (ML D)、狭窄度 (DS)、再狭窄率、即刻管腔获得 (AL G)、即刻血管弹性回缩 (AR)及弹性回缩率 (ARR)。结果　术后即刻 ML D、DS、AL G两组差异无显著性。 CBA组最大扩张压、AR及 ARR均较 POBA组低 (P<0 .0 5或 P<0 .0 0 1)。随访造影结果 ,CBA组 ML D明显大于 POBA组 (P<0 .0 5 ) ;DS及再狭窄率均小于 POBA组 (P<0 .0 1)。结论　 CBA组的低压扩张治疗支架内再狭窄病变是有效的 ,对血管损伤小于 POBA,且获得较 POBA低的再狭窄率 ,值得进一步探讨

Comparison the early and late treatment effect of plain old balloon angioplasty and cutting balloon angioplasty on coronary in-stent restenosis

Objective By comparing the early and late coronary angiograms results between cutting balloon angioplasty(CBA) and plain old balloon angioplasty(POBA),to evaluate the efficacy of CBA on coronary in-stent restenosis.Methods 37 patients with in-stent restenosis after patients underwent PTCA, of which 39 lesions were enrolled in this study,mathed with 23 lesions in CBA group, with 16 lesions in POBA group. The instant and late minimal lumen diameters(MLD),diameter stenoses(DS),and restenosis rates as well as acute lumen gain(ALG),acute recoil(AR) and acute recoil rate(ARR) after PTCA in two groups were compared. Results Although no significant difference in MLD,DS and ALG was observed instantly after the procedure between the two groups. the balloon inflation pressure,AR and ARR in CBA group was significantly lower in CBA than those in POBA group (P<0.05 or P<0.001). At follow-up angiography, the MLD in CBA group was significantly longer than that in POBA group (P< 0.05); but the DS and the restenosis rates in CBA group was significantly lower than in POBA(P< 0.01).Conclusion Angioplasty with CB for in-stent restenosis,requires the lower pressure and canses less vessel injury and might significantly decrease the restenosis rate.