尿路感染病原菌分布及耐药性检测

目的 探讨尿路感染病原菌的分布及耐药性特征，为临床合理选用抗生素、控制医院感染提供依据。方法 收集我院尿路感染患者标本中分离的151株病原菌进行鉴定，同时对G^-杆菌进行ESBLs的检测，肠球菌属进行氨基糖昔类高水平耐药(HLAR)的筛选。结果 尿路感染病原菌分布占前几位的细菌为大肠埃希菌53．64％、肠球菌属9．27％、凝固酶阴性葡萄球菌7．95％、假单胞菌5．96％；产ESBLs大肠埃希菌的检出率为13．58％，产ESBLs肺炎克雷伯菌的检出率为16．67％，HLAR肠球菌属检出率为57．14％。结论 重视尿路感染病原菌耐药性检测，对控制医院感染、合理使用抗生素十分重要。

Distribution of Pathogens and Resistance Detection in Urinary Infection

OBJECTIVE To determine distribution of pathogens and resistance characteristic and to provide basis for clinicians to select antibiotics correctly and control nosocomial infection. METHODS A total of 151 strains of pathogens were identified. ESBLs-producing G - bacteria were detected and high-level aminoglycoside resistance in Enterococcus(HLAR) were screened. RESULTS Among 151 strains, 53.64% Escherichia coli, 9.27% Enterococcus, 7.95% coagulase negative Staphylococcus and 5.96% Pseudomonas were detected. 13.58% E.coli and 16.67% Klebsiella pneumoniae produced ESBLs. HLAR-producing Enterococcus was 57.14%. CONCLUSIONS Much attention should be paid to resistance detection in urinary infection. It is important to control nosocomial infection and select antibiotics correctly.