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脱细胞异体真皮基质皮下移植后胶原的动态变化
引用本文:霍孟华,戚可名,黄金井,管正玉,庄强,王阳,吕晓岩.脱细胞异体真皮基质皮下移植后胶原的动态变化[J].中华整形外科杂志,2004,20(1):51-52.
作者姓名:霍孟华  戚可名  黄金井  管正玉  庄强  王阳  吕晓岩
作者单位:100041,北京,中国医学科学院中国协和医科大学整形外科医院
摘    要:目的 探讨脱细胞异体真皮基质 (ADM)移植后胶原的变化情况。方法 将异体ADM移植于SD鼠皮下 ,测定移植后ADM中胶原的含量及Ⅰ、Ⅲ型胶原的比例。结果 异体ADM移植后胶原含量及Ⅰ、Ⅲ型胶原比例无明显变化。结论 异体ADM是一种良好的软组织填充材料。

关 键 词:脱细胞真皮基质  移植  胶原
修稿时间:2002年8月21日

Collagen changes of allografting an aceilular dermal matrix
Meng-hua Huo,Ke-ming Qi,Jin-jing Huang,Zheng-yu Guan,Qiang Zhuang,Yang Wang,Xiao-Yan Lü.Collagen changes of allografting an aceilular dermal matrix[J].Chinese Journal of Plastic Surgery,2004,20(1):51-52.
Authors:Meng-hua Huo  Ke-ming Qi  Jin-jing Huang  Zheng-yu Guan  Qiang Zhuang  Yang Wang  Xiao-Yan Lü
Institution:Plastic Surgery Hospital of Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100041, China.
Abstract:Objective To evaluate the collagen changes of allografting an acellular dermal matrix (allo-ADM). Methods The allo-ADM was grafted underneath the skin of SD rats. The content of collagen and the proportion of type I to III collagen was examined with a biochemical assay.Result The content of collagen and the proportion of type I to III collagen in the allo-ADM group showed no significant changes. Conclusion The allo-ADM could keep long time in the body and it may be an ideal material for soft tissue filling.
Keywords:Acellular dermal matrix  Transplantation  Collagen
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