成年人吸烟状态与糖化血红蛋白及胰岛素的关系

目的 探讨成年人不同吸烟状态与糖化血红蛋白（HbA1c）和胰岛素水平的关系。方法 多阶段分层随机整群抽样的方法抽取徐州地区18岁及以上的常住居民，进行问卷调查、体格测量和实验室检查。多元线性回归模型分析吸烟状态与HbA1c及胰岛素水平之间的关系。结果 HbA1c水平的比较显示，被动吸烟组和不吸烟且无被动吸烟组的HbA1c均低于现在吸烟组（P＜0.01），曾经吸烟组、被动吸烟组和不吸烟且无被动吸烟组的服糖后2 h胰岛素均高于现在吸烟组的服糖后2 h胰岛素（P＜0.01）。结论 吸烟和被动吸烟可能是引起HbA1c异常的相关因素。

Association between smoking status and the level of HbA1c and insulin in the adults

Objective The aim of this study was to explore the correlation between smoking status and HbA1c and insulin in the adults. Methods The residents aged 18 years old and above living in Xuzhou city were sampled by the multi-stage stratified random cluster sampling. The questionnaire interview, physical examination and laboratory tests were carried out on the participants. Multiple linear regression model was used for the analysis of correlation between smoking status and level of HbA1c and insulin. Results The comparison of HbA1c levels showed that the passive smoking group and the no smoking without passive smoking group had lower levels of HbA1c than that of the current smoking group(P<0.01). The ex-smoking group, the passive smoking group and the no smoking without passive smoking group had higher insulin levels two hours after 75g OGTT than the current smoking group(P<0.01). Conclusion Current smoking and passive smoking may be associated with HbA1c abnormalities.