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Distinct Osteomimetic Response of Androgen‐Dependent and Independent Human Prostate Cancer Cells to Mechanical Action of Fluid Flow: Prometastatic Implications
Authors:Álvaro González  Cira García de Durango  Verónica Alonso  Beatriz Bravo  Arancha Rodríguez de Gortázar  Alan Wells  Jerónimo Forteza  Fernando Vidal‐Vanaclocha
Affiliation:1. Department of Molecular and Cellular Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas;2. Institute of Applied Molecular Medicine (IMMA), CEU‐San Pablo University School of Medicine, Madrid, Spain;3. Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania;4. Valencia Institute of Pathology, Catholic University of Valencia School of Medicine and Odontology, Valencia, Spain
Abstract:
Keywords:osteomimicry  prostate cancer  androgen resistance  osteocyte  cancer microenvironment  metastasis  angiogenesis  tumor interstitial fluid flow  mechanical stimulation  bone remodeling  gene expression
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