彩色速度成像及定量技术在脑梗死疾病中的应用

目的 :探讨彩色速度成像及定量技术 (CVI- Q )评价脑梗死患者的脑血流动力学变化的价值。 方法 :采用 CVI- Q技术检查 6 0例正常人和 40例脑梗死患者的双侧颈总动脉 ,观察颈总动脉走行、内膜厚度、有无粥样硬化斑片 ,测量血管内径(d) ,峰值血流速度 (Vmax) ,阻抗系数 (RI)和血流量 (Q)。结果 :脑梗死组中 75 %的患者均有不同程度的内膜增厚 ,45 %的患者有颈总动脉粥样硬化斑片 ,且 71%的斑片位于膨大及分叉处。脑梗死患者各项测值与正常组对照结果显示 :(1)颈总动脉 d较正常人明显增宽 (P<0 .0 5及 P<0 .0 1) ;(2 )颈总动脉 Vmax较正常人明显降低 (P<0 .0 5 ) ;(3)颈总动脉 RI较正常人明显升高(P<0 .0 5及 P<0 .0 1) ;(4 )颈总动脉 Q较正常人明显降低 (P<0 .0 1)。结论 :CVI- Q技术可用于检测脑梗死患者脑血流动力学改变 ,为临床脑梗死缺血程度及治疗效果的评价提供有价值的量化指标。

Application of color velocity imaging-quantitative method in cerebral infarction

Objective: To evaluate color velocity imaging quantitative method (CVI Q) in estimating cerebral hemodynamic change in patients with cerebral infarction. Methods: The carotids of 60 normal people and 40 cerebral infarction patients were detected by CVI Q. We observed endangium thickness and atheromatous plaques,and measured the diameter ( d ), peak velocity( V max ), resistance index(RI) and blood flow volume( Q ) of the common carotid arteries. Results: In cerebral infarction group there were 75% cases with endangium thickening to different degrees, 45% cases with atheromatous plaques and 71% plaques in carotid enlargement section or bifurcation. The data measured in 2 groups were compared: (1)The d value in cerebral infarction cases increased than that in normal( P <0.05 or P <0.01); (2)The V max reduced in cerebral infarction cases( P <0.05); (3)The RI increased in cerebral infarction cases ( P <0.05 or P < 0.01); (4) The Q value reduced in cerebral infarction cases ( P <0.01). Conclusion: CVI Q can be used for detecting cerebral hemodynamic changes and provide quantitative indexes for clinicians to estimate ischemia degree and treatment in cerebral infarction patients. [