| 肥胖儿童T淋巴细胞亚群的功能评估 |
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| 引用本文： | 汤庆娅,冯一,陶晔璇,费延文,蔡威.肥胖儿童T淋巴细胞亚群的功能评估[J].中国临床营养杂志,2005,13(3):154-156. |
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| 作者姓名： | 汤庆娅 冯一 陶晔璇 费延文 蔡威 |
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| 作者单位： | 1. 上海第二医科大学,附属新华医院,上海儿童医学中心临床营养中心,上海,200092
2. 上海市儿科医学研究所营养研究室,上海 |
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| 摘 要： | 目的了解肥胖儿童的细胞免疫功能状态。方法2002年4月～2003年10月,共采集我院肥胖专科门诊儿童和青少年的单纯性肥胖患儿47例,其中男30例,女17例,平均年龄(11.4±2.2)岁;同期随机抽取37名正常体重学生的健康自愿者作为对照组,其中男16例,女21例,平均年龄(13.4±1.0)岁。采集肘部静脉血,采用流式细胞仪进行T淋巴细胞的亚群分析。结果肥胖组的T淋巴细胞亚群CD3+、CD4+、CD8+和CD4+/CD8+与对照组相比,差异均无显著性(均P>0.05);且CD3+、CD4+、CD8+和CD4+/CD8+与肥胖程度无相关性(r分别为-0.012、-0.102、0.139、-0.103,均P>0.1)。正常组CD3+、CD4+、CD8+和CD4+/CD8+与体重也无相关性(r分别为-0.223、-0.076、-0.190、-0.072,均P>0.1)。结论肥胖患儿T淋巴细胞亚群的免疫功能无减退现象。
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| 关 键 词： | 肥胖 儿童 T细胞亚群 |
| 文章编号： | 1008-5882(2005)03-0154-03 |
| 修稿时间： | 2005年4月21日 |
Functional Evaluation of Immunologically Competent Cell in Obese Children and Adolescents |
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| Tang Qing-ya#,Feng Yi,Tao Ye-xuan,Fei Yan-wen,Cai Wei.Functional Evaluation of Immunologically Competent Cell in Obese Children and Adolescents[J].Chinese Journal of Clinical Nutrition,2005,13(3):154-156. |
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| Authors: | Tang Qing-ya# Feng Yi Tao Ye-xuan Fei Yan-wen Cai Wei |
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| Institution: | Tang Qing-ya#,Feng Yi,Tao Ye-xuan*,Fei Yan-wen,Cai Wei |
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| Abstract: | Objective To understand the function of immunologically competent cell in obese children and adolescents. Methods The plasms T- lymphocyte subsets of 84 children and adolescents(47 obese and 37 normal, 46 boys and 38 girls) were examined, including CD3+, CD4+, and CD8+ T-lymphocyte cells. Results The plasma T-lymphocyte subsets count percent of 47 obese children and adolescents had not statistical significance compare with the normal group(P > 0.05), and the value of CD3+, CD4+,CD8+ and the rate of CD4+/CD8+ apart were not correlated with the obesity degree(r = -0.012, -0.102, 0.139, and -0.103, P > 0.1). Conclusion No functional impairment of T-lymphocytes immunity exists in obese children and adolescents. |
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| Keywords: | obesity children T-lymphocytes subset |
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