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大动脉转换术治疗新生儿完全性大动脉错位
引用本文:徐志伟,丁文祥,苏肇伉.大动脉转换术治疗新生儿完全性大动脉错位[J].中华胸心血管外科杂志,2002,18(3):147-149.
作者姓名:徐志伟  丁文祥  苏肇伉
作者单位:200127,上海第二医科大学附属新华医院,上海儿童医学中心心胸外科
摘    要:目的 回顾总结完全性大动脉错位(D-TGA)的手术治疗。方法 1999年11月至2001年8月,采用大动脉转换术(Switch)手术方法纠治新生儿D-TGA 16例,其中室间隔完整型大动脉错位(D-GA/IVS)6例,大动脉错位伴室间隔缺损(D-TGA/VSD)10例。所有病例都在深低温低流量和深低温停循环下行Switch纠治术。结果 Switch手术治疗TGA共16例,其中TGA/IVS 6例,无死亡;TGA/VSD 10例,死亡2例,均为伴有冠状动脉畸形者。14例随访2-20个月,VSD残余漏1例,肺动脉轻度残余梗阻2例,14例心功能均良好。结论 Switch手术是D-TGA纠治的首选方法,但必须早期手术。

关 键 词:大动脉转换术  新生儿安全性大动脉错位  先天性心脏缺损  冠状血管畸形  心脏外科
修稿时间:2001年9月26日

Arterial Switch operation for complete transposition of great arteries in neonates
XU Zhiwei,DING Wenxiang,SU Zhaokang.Arterial Switch operation for complete transposition of great arteries in neonates[J].Chinese Journal of Thoracic and Cardiovascular Surgery,2002,18(3):147-149.
Authors:XU Zhiwei  DING Wenxiang  SU Zhaokang
Institution:XU Zhiwei,DING Wenxiang,SU Zhaokang. Department of Thoracic and Cardiovascular Surgery,Shanghai Children's Medical Center,Xinhua Hospital,Shanghai Second Medical University,Shanghai 200127,China
Abstract:Objective: To review and summarize the experience of surgical repair of transposition of great arteries (D TGA). Methods: Sixteen patients with TGA were treated by arterial Switch operation during November 1999 to August 2001. There were 6 patients with transposition of great arteries and intact ventricular septum (D TGA/IVS), and 10 patients with transposition of great arteries and ventricular septum defect (D TGA/VSD). The operation was carried out under deephypothermia circulatory arrest and low flow perfusion. Results: There were 2 deaths with mortality rate of 12.5%. The two deaths occurred in all patients with D TGA/VSD with abnormal coronary arteries. 14 patients were follow up from 2 months to 20 months. There were one residual VSD and two mild pulmonary obstructions. All patients had good heart function. Conclusion: The Switch operation can be considered ass the first choice for surgical repair of D TGA in neonates, and should be performed as early as possible.
Keywords:Heart defects  congenital    Coronary vessel anomalies    Cardiac surgical procedures
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