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耳鼻咽喉科领域的软骨组织工程
引用本文:孙安科,裴国献,陈文弦,李湘平.耳鼻咽喉科领域的软骨组织工程[J].中国耳鼻咽喉颅底外科杂志,2003,9(3):188-191.
作者姓名:孙安科  裴国献  陈文弦  李湘平
作者单位:1. 第一军医大学南方医院全军创伤骨科中心,广东,广州,510515
2. 第四军医大学唐都医院,耳鼻咽喉科,陕西,西安,710038
3. 第一军医大学南方医院,耳鼻咽喉科,广东,广州,510515
基金项目:国家重点基础研究发展规划(973)(G1999054509),中国博士后科学基金(中博基[2002]11号),广州市科委攻关项目(2000Z0170)
摘    要:耳、鼻、喉和气管的软骨组织工程研究已有较大进展,已分别在裸鼠和具有免疫力动物体内形成了与耳鼻咽喉有关的组织工程化软骨组织,并有初步应用的实验研究报道。随着胚胎干细胞、骨髓基质干细胞、同种异体软骨细胞和智能生物材料的研发和应用,耳鼻咽喉科软骨组织工程有望获得突破性进展。本文综述了该领域的软骨组织工程研究现状和发展趋势。

关 键 词:耳鼻咽喉科  软骨组织工程  同种异体软骨细胞  智能生物材料
文章编号:1007-1520(2003)03-0188-04
修稿时间:2002年6月28日

Cartilage tissue engineering in otorhinolaryngology
SUN An-ke,PEI Guoxian,CHEN Wen-xian,et al..Cartilage tissue engineering in otorhinolaryngology[J].Chinese Journal of Otorhinolaryngology-skull Base Surgery,2003,9(3):188-191.
Authors:SUN An-ke  PEI Guoxian  CHEN Wen-xian  
Abstract:There were many significant achievements in tissue engineering research on otorhinolaryngological cartilage. Tissue engineered auricular, nasal and trachea! cartilage not only were obtained in athymic nude mice and animals with immunity but also have been initially used to repair cartilage defects in animals. In the near future, with the development and application of embryonic stem cells (ES) , bone marrow mesenchymal stem cells (MSCs) , allogeneic chondrocytes and smart biomaterials, it is hopeful for cartilage tissue engineering to achieve breakthrough results in otorhinolaryngology. The article reviewed and summarized the present research and progress on cartilage tissue engineering in otorhinolaryngology.
Keywords:Otorhinolaryngology  Cartilage tissue engineering  Review Literature
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