气相色谱法测定小金胶囊中麝香酮的含量

目的 建立小金胶囊中麝香酮的含量测定方法. 方法采用AT.OV 1301色谱柱(30 m×0.25 mm,0.25 μm);起始温度200 ℃,维持10 min,以30 ℃.min^-1的速率升温至250 ℃,维持10 min;进样口温度为200 ℃;检测器:氢火焰离子化检测器;检测器温度为280 ℃. 结果 麝香酮进样量在46～736 ng的范围内线性关系良好(r＝0.999 8),平均回收率为100.10%(RSD＝ 1.61%). 结论 该方法操作简便、快速、准确,可作为小金胶囊质量控制的方法.

Content Determination of Muscone in Xiaojin Capsules by Gas Chromatography

Objective To establish a method for content determination of muscone in xiaojin capsules.Methods AT.OV-1301 column(30 m×0.25 mm,0.25 μm) was applied,the initial temperature of oven was set at 200 ℃ for 10 minutes,then it was raised to 250 ℃ for 10 minutes at rate of 30 ℃ per minute.The temperature of injection port was 200 ℃.The detector was FID,which was at 280 ℃.Results The calibration curves were linear in the range of 46-736 ng for muscone(r=0.999 8).The average recovery was 100.10%(RSD=1.61%).Conclusion The method is simple,rapid,accurate,which can be used for the quality control of xiaojin capsules.