组织再生研究进展

几百年来,人们一直对自然界中的再生现象怀有极大的兴趣.随着分子生物学研究手段的发展,人们在分子水平上对再生的机制有了更深入的认识.目前对两栖类再生的分子机制研究已经越来越深入,而且越来越多的实验证明哺乳类动物也具有再生能力,至少两栖类和哺乳类在损伤修复中的机制可能是保守的.因此,对再生的机制研究有可能在临床上为损伤修复带来更好的治疗手段.本文希望通过对蝾螈附肢与哺乳动物再生能力及机制研究的介绍,使读者能对这一领域有初步的认识.

Progress of research on tissue regeneration

For hundreds of years, scientists have been inspired by the regeneration phenomena in nature. Thanks to the development in the research tools for molecular biology, our understanding of the underlying molecular mechanisms involved in regeneration has been greatly deepened. Besides the increasing knowledge obtained from the studies on the molecular mechanisms of amphibian regeneration, accumulating evidence has proved that mammals may also have regenerative property, and the repair mechanisms should be conserved cross the species. Therefore, better clinical therapies are expected with the elucidation of regeneration mechanisms. Through introduction of the recent progress in amphibian appendage and mammalian regeneration, we expect the readers to have the fundamental understanding in this promising field.