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复方玉屏风超声提取工艺
引用本文:杨鼎隆,李育民,黄晓君,黄敏霞,贲永光. 复方玉屏风超声提取工艺[J]. 中国实验方剂学杂志, 2012, 18(5): 17-19
作者姓名:杨鼎隆  李育民  黄晓君  黄敏霞  贲永光
作者单位:广东药学院药科学院,广州,510006
基金项目:广东省高等学校大学生创新实验项目(1057310018);广东省科技计划项目(2009A030100007);企业科技特派员工作站建设项目(2010B090500033);中国科学院海洋生物资源可持续利用重点实验室、广东省海洋药物重点实验室、广东省应用海洋生物学重点实验室联合开放基金项目(LMB081003)
摘    要:目的:探讨超声强化提取玉屏风总糖的最佳工艺条件,比较玉屏风总糖的复方和单方提取的优劣.方法:利用正交设计试验确定玉屏风总糖最佳提取工艺,与常规提取方法进行比较,并比较玉屏风总糖的复方整体和单方提取率.结果:结果表明最佳工艺条件为固液比1∶20,超声温度55℃,超声时间20 min,此优化条件下,复方玉屏风总糖的提取率为14.25%,浸渍180 min的提取率为5.44%,常规搅拌180 min的提取率为7.35%.结论:与传统提取方法(浸渍法和搅拌法)比较,超声提取具有省时、节能、高效等优点,为现代药企进行大规模、高效率的生产提供了充分条件.

关 键 词:玉屏风总糖  超声提取  正交试验
收稿时间:2011-09-22

Ultrasonic-assisted Extraction Process of Compound Yupingfeng
YANG Ding-long,LI Yu-min,HUANG XIAO-jun,HUANG Min-xia and BI Yong-guang. Ultrasonic-assisted Extraction Process of Compound Yupingfeng[J]. China Journal of Experimental Traditional Medical Formulae, 2012, 18(5): 17-19
Authors:YANG Ding-long  LI Yu-min  HUANG XIAO-jun  HUANG Min-xia  BI Yong-guang
Affiliation:College of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China;College of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China;College of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China;College of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China;College of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China
Abstract:Objective:To investigate optimum extraction technology conditions of polysaccharides from Yupingfeng by ultrasonic-assisted extraction,and to compare extraction rate of polysaccharides between compound extraction and unilateral extraction.Method:Optimum extraction conditions were obtained by orthogonal design test,compared with traditional extraction technology,and compared extraction rate of polysaccharides from Yupingfeng by compound extraction and unilateral extraction.Result: Result showed that optimum technology conditions were:ultrasound temperature 55 ℃,ratio of solid-liquid 1∶20,ultrasonic time 20 min,under these optimum conditions,extraction rate of polysaccharides from Yupingfeng was 14.25%,extraction rate of impregnation method was 5.44% in 180 min,extraction rate of conventional mixing method was 7.35%.Conclusion: Compared with traditional extraction methods(impregnation method and mixing method),ultrasonic extraction had some advantages,such as time-saving,energy saving,high efficiency and so on.It offered sufficient conditions for large-scale and efficient production of modern medicine enterprises.
Keywords:polysaccharides from compound Yupingpeng  ultrasound extraction  orthogonal experiment
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