Selective photoreceptor cell loss in hypoxic ischemia |
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| Authors: | R E Holman R L Peiffer T W Bouldin B S Grimson |
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| Affiliation: | Department of Ophthalmology, School of Medicine, University of North Carolina, Chapel Hill 27599-7040. |
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| Abstract: | We studied the histopathologic changes in the brain and eye of a 5 1/2-month-old infant who suffered a profound hypotensive episode three days antemortem. Nuclear pyknosis and other histologic changes characteristic of ischemic cell necrosis were found throughout the brain and in the retina's photoreceptor-cell layer. These findings suggest that hypoxic ischemia may produce preferential damage to the photoreceptor-cell layer. |
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