Decrease in neutrophils observed in vivo in psoriatics after PUVA therapy |
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| Authors: | K B Dahl A Nyfors H Brodthagen |
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| Institution: | (1) Department of Dermatology, the Finsen Institute, 49 Strandboulevarden, DK-2100 Copenhagen Ø, Dermark |
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| Abstract: | Summary In 56 patients leucocyte and differential counts were done before and at weekly intervals during PUVA treatment of chronic recalcitrant psoriasis. A statistical significant (P<0.01) decrease in the percentage of neutrophils was observed during the first week of the PUVA therapy. This observation could be closely related to the clinical clearing of psoriasis (P=0.02).The effect of PUVA therapy in psoriasis may be due to a decrease in the number of immunocompetent neutrophils demonstrated in psoriatic lesions. |
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| Keywords: | Psoriatics PUVA-Neutrophils Leucocytes |
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