| 精子畸形率对卵胞浆内单精子注射(ICSI)临床结局的影响 |
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| 引用本文： | 王国贺,郭艺红,孙莹璞,苏迎春,金海霞,王杨.精子畸形率对卵胞浆内单精子注射(ICSI)临床结局的影响[J].生殖与避孕,2011,31(4):241-245. |
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| 作者姓名： | 王国贺 郭艺红 孙莹璞 苏迎春 金海霞 王杨 |
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| 作者单位： | 郑州大学第一附属医院生殖中心,郑州,450052 |
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| 摘 要： | 目的:分析畸形精子行卵胞浆内单精子注射(ICSI)的临床结局。方法:回顾性分析因男性因素行ICSI治疗的239个新鲜取卵周期。根据精子形态学分析结果将研究对象分为:精子形态正常组(A组)、非极重度畸形精子症组(B组)和极重度畸形精子症组(C组),比较3组的受精率、卵裂率、优质胚胎率、胚胎种植率及临床妊娠率、流产率、异位妊娠率和多胎妊娠率。结果:A、B组在受精率、卵裂率、优质胚胎率与C组有统计学差异(分别为80.20%、81.40%和67.60%;94.91%、93.42%和79.91%;63.87%、59.30%和54.29%)(P<0.05);3组的胚胎种植率、临床妊娠率、流产率、异位妊娠率、多胎妊娠率均无统计学差异(分别为26.3%、25.6%和24.2%;42.28%、45.00%和42.86%;7.94%、7.40%和25.00%;4.76%、3.70%和8.33%;31.75%、18.52%和25.00%)(P>0.05);而C组内手术取精(PESA/TESA)亚组的卵裂率低于体外排精亚组,差异有统计学意义(86.72%vs 76.11%,P<0.05)。结论:采用畸形精子行ICSI的不育患者同样可获得理想的临床结局。
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| 关 键 词： | 畸形精子 卵胞浆内单精子注射(ICSI) 临床结局 |
Impact of Sperm Malformation Rate on ICSI Clinical Outcomes |
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| Guo-he WANG,Yi-hong GUO,Ying-pu SUN,Ying-chun SU,Hai-xia JIN,Yang WANG.Impact of Sperm Malformation Rate on ICSI Clinical Outcomes[J].Reproduction and Contraception,2011,31(4):241-245. |
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| Authors: | Guo-he WANG Yi-hong GUO Ying-pu SUN Ying-chun SU Hai-xia JIN Yang WANG |
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| Institution: | Guo-he WANG,Yi-hong GUO,Ying-pu SUN,Ying-chun SU,Hai-xia JIN,Yang WANG(Reproductive Medical Center of the First Affiliated Hospital of Zhengzhou University,Zhengzhou,450052) |
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| Abstract: | Objective:To evaluate the efficacy of intracytoplasmic sperm injection(ICSI) in the treatment for teratospermia.Methods:A total of 239 cycles received ICSI because of male factors was analyzed by a retrospective study.They were divided into 3 groups:group A(normal sperm forms group),group B(not severe teratospermia group) and group C(severe teratospermia group).All the infertility patients were diagnosed by sperm morphology before ICSI.The rates of fertilization,cleavage,good quality embryos,embryo implanta... |
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| Keywords: | teratospermia intracytoplasmic sperm injection outcomes |
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