| 高雄激素血症与多囊卵巢综合征中非酒精性脂肪性肝病的关系 |
| |
| 引用本文： | 曲中玉,石玉华,陈子江. 高雄激素血症与多囊卵巢综合征中非酒精性脂肪性肝病的关系[J]. 生殖与避孕, 2011, 31(1): 14-17 |
| |
| 作者姓名： | 曲中玉 石玉华 陈子江 |
| |
| 作者单位： | 1. 山东大学附属省立医院超声诊疗中心,济南,250021
2. 山东大学附属省立医院生殖中心,济南,250021 |
| |
| 摘 要： | 目的:探讨高雄激素血症(HT)与多囊卵巢综合征(PCOS)患者非酒精性脂肪性肝病(NAFLD)发病的关系。方法:对306例PCOS患者进行基础内分泌、口服糖耐量试验及胰岛素释放试验、肝功能、血脂等检查,B超诊断脂肪肝。结果:306例PCOS患者中诊断出NAFLD94例,发病率为30.7%;其中NAFLD轻度56例(59.6%),中度34例(36.2%),重度4例(4.2%)。PCOS患者NAFLD的发病率与HA无明显相关性,与稳态模型评估胰岛素抵抗指数(HOMA-IR)、甘油三酯(TG)呈正相关。PCOS合并NAFLD组胰岛素抵抗(IR)发生率明显高于PCOS不合并NAFLD组,P<0.05;PCOS高雄激素血症(PCOS-HA)组IR发生率与PCOS非高雄激素血症(PCOS-NHA)组无明显差异,P>0.05。结论:PCOS患者NAFLD发病率较高,PCOS患者NAFLD的发生与IR、代谢异常密切相关,与HA无明显相关。
|
| 关 键 词： | 多囊卵巢综合征(PCOS) 非酒精性脂肪性肝病(NAFLD) 胰岛素抵抗(IR) 高雄激素血症(HA) |
Hyperandrogenemia Relation to Nonalcoholic Fatty Liver Disease in Chinese Women with Polycystic Ovary Syndrome |
| |
| Zhong-yu QU,Yu-hua SHI,Zi-jiang CHEN. Hyperandrogenemia Relation to Nonalcoholic Fatty Liver Disease in Chinese Women with Polycystic Ovary Syndrome[J]. Reproduction and Contraception, 2011, 31(1): 14-17 |
| |
| Authors: | Zhong-yu QU Yu-hua SHI Zi-jiang CHEN |
| |
| Affiliation: | Zhong-yu QU1,Yu-hua SHI2,Zi-jiang CHEN2(1.Ultrasound center,Provincial Hospital affiliated to Shandong University,Jinan,250021)(2.Reproductive medicine center,250021) |
| |
| Abstract: | Objective:To investigate the relationship between hyperandrogenemia(HA) and nonalcoholic fatty liver disease(NAFLD) in women with polycystic ovary syndrome(PCOS).Methods:Patients data came from 306 women with PCOS by Rotterdam consensus criteria.Basal endocrine,oral glucose tolerance test(OGTT),insulin release test,lipid profile,blood pressure and body mass index(BMI) were tested.Liver chemistries,B-hepatitis and C-hepatitis were performed,and alcoholic liver diseases were excluded.Fatty liver was diagnosed... |
| |
| Keywords: | polycystic ovary syndrome(PCOS) nonalcoholic fatty liver disease(NAFLD) insulin resistance(IR) hyperandrogenemia(HA) |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
