| 减少GnRHa剂量对长方案促排卵卵巢反应性的影响 |
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| 引用本文： | 王慧焱,孙海翔,王玢,陈华. 减少GnRHa剂量对长方案促排卵卵巢反应性的影响[J]. 生殖与避孕, 2010, 30(9): 638-640 |
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| 作者姓名： | 王慧焱 孙海翔 王玢 陈华 |
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| 作者单位： | 南京大学医学院附属鼓楼医院生殖医学中心,南京,210008 |
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| 摘 要： | 目的:探讨减少GnRHa剂量对长方案促排卵的卵巢反应性影响。方法:对37例采用长方案进行促排卵且第一周期未妊娠或流产的患者进行自身对照研究,第一个周期GnRHa用量为0.05mg/d,第二个周期GnRHa用量为0.03mg/d。结果:Gn使用天数、Gn用量、受精率第一、第二促排卵周期间无显著性差异(P>0.05)。获卵数、可移植胚胎数第二周期组较第一周期组显著增加(P<0.05)。结论:本研究认为在长方案促排卵过程中减少GnRHa的剂量可以增加获卵数,改善卵巢反应性,增加IVF妊娠率。
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| 关 键 词： | GnRHa 剂量 长方案 体外受精-胚胎移植(IVF-ET) |
Effects of Reducing Dose of GnRHa on Ovarian Response with Long Protocol in Controlled Ovarian Hyperstimulation |
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| Hui-yan WANG,Hai-xiang SUN,Bin WANG,Hua CHEN. Effects of Reducing Dose of GnRHa on Ovarian Response with Long Protocol in Controlled Ovarian Hyperstimulation[J]. Reproduction and Contraception, 2010, 30(9): 638-640 |
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| Authors: | Hui-yan WANG Hai-xiang SUN Bin WANG Hua CHEN |
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| Affiliation: | (Reproductive Medical Center,Nanjing Drum Tower Hospital Affiliated to the Medical School of Nanjing University,Nanjing,210008) |
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| Abstract: | Objective：To study the effects of reducing dose of GnRHa on ovarian response with long protocol in controlled ovarian hyperstimulation（COH）.Methods：A self controlled analysis was performed on a total of 37 IVF patients who were treated with long protocol in COH.The first cycle GnRHa dose was 0.05 mg/d and IVF outcomes were failure or abortion.The second cycle GnRHa dose was 0.03 mg/d.Results：No significant differences were observed in stimulation days,gonadotrophin ampoules and fertilization rate.The number of oocyte retrieved,the number of embryo that could be transferred of the second cycle were higher than those of the first cycle.Conclusion：Reducing dose of GnRHa in long protocol of COH could increase the number of oocyte retrieved, improve ovarian response and IVF outcome. |
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| Keywords: | GnRHa |
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