Aging of the erythrocyte XVII. Binding of autologous immunoglobulin G

Increased amounts of autologous immunoglobulin (Ig) G were found on older bovine erythrocytes employing ¹²⁵I-labelled Protein A, ¹²⁵I-labelled anti(bovine IgG) antibodies and hemolysis in the presence of anti(bovine IgG) antibodies + complement. In vitro, desialylation, proteolysis and action of an O₂$\text{·}$ source but not glycosylation induced binding of extraneous IgG to the erythrocytes.