极早早产儿早期持续鼻饲输注喂养预防早产儿喂养不耐受

目的：探讨早期持续鼻饲输注喂养能否降低胎龄为25-28周的极早早产儿喂养不耐受的发病率。方法：将2009年12月-2011年12月本科孕龄25-28周的极早早产儿在生后24h内随机分配到早期持续鼻饲输注喂养组（简称持续喂养组，共29名）或早期间歇推注喂养组（简称间歇喂养组，共30名），观察两组喂养不耐受发生率。结果：持续喂养组婴儿喂养不耐受发生率为6．9％，间歇喂养组为53-3％．两组比较差异有统计学意义OR=0．065；95％CI（0．013，0．323）；P=0.000]。结论：早期持续鼻饲输注喂养较早期间歇推注喂养更能降低胎龄25-28周的极早早产儿喂养不耐受的发病率。

Early Continuous Nasogastric Infusion Feeding for Prevention of Feeding Intolerance of Extremely Premature Infants

Objective：To explore whether early continuous nasogastric infusion feeding can reduce the incidence of feeding intolerance of extremely premature infants with a gestational age of 25 to 28 weeks.Methods： From December 2009 to December 2011, 59 cases of extremely premature infants with a gestational age of 25 to 28 weeks within 24 hours after birth were randomly divided into early continuous nasogastric infusion feeding group （29 infants）and early intermittent nasogastric feeding group （30 infants）, then the incidence of feeding intolerance were observed and compared .Results： The incidence of feeding intolerance in early continuous nasogastric infusion feeding group was 6.9%, and 53.3% in early intermittent nasogastric feeding group OR=0.065, 95% CI （0.013, 0.323）, P=0.000]. Conclusion：Early continuous nasogastric infusion feeding can reduce the incidence of feeding intolerance of extremely premature infants with a gestational age of 25 to 28 weeks.