焦炉作业多环芳烃暴露工人诱发电位检测

目的 检测多环芳烃暴露人群诱发电位的变化情况。方法 按炉顶、炉侧、炉底不同作业岗位各随机选取15名焦炉工为暴露组,另选一般情况相近的25名库工为对照组。高效液相色谱法检测研究对象尿中1-羟基芘水平;Neuropack M1肌电图仪进行体感诱发电位(SEP)、听觉诱发电位(AEP)和视觉诱发电位(VEP)的测定。结果 尿中1-羟基芘对照组、炉底组、炉侧组、炉顶组分别为(2.71±0.22),(3.29±0.38),(3.63±0.55),(4.13±0.62)μmol/mol Cr,呈现炉顶>炉侧>炉底>对照的趋势;各组体感诱发电位、听觉诱发电位和视觉诱发电位各指标经方差分析,差异无统计学意义(P<0.05)。结论 在目前的接触水平下,多环芳烃暴露人群躯体感觉传导通路、听觉传导通路和视觉传导通路未发生明显异常。

Determination of evoked potential in coke oven workers

Objective To explore the effect of polycyclic aromatic hydrocarbons on the evoked potential in coke oven workers.Methods Forty five healthymale coke oven workers were selected randomly froma coke plant of a state owned steel enterprise in Taiyuan city according to their work sites.Twenty five controls of unexposed to poly cyclic aromatic hydrocarbons(PAHs)occupationally were selected from the same enterprise.Urine samples were collected mimediately after working shift.The level of urinary 1 hydroxypy rene was determined by High Performance Liquid Chromatography (H-PLC).General information of workers correlated with the investigation was collected with questionnaire by trained in terviewers.The sensory,aud itory and patternvisual evoked potentials were monitored by neuqopack M 1(Nihon Kohden corporation).Results No significant difference was found among four groups of different age,length of service,smoking,drinking,educational level and unhealthy food consumption.Urinary 1 hydroxypyrene were significant diffenert among four groups,with a tendency of oven top>oven side>oven bottom>control.Compared with the controls,there was no significant difference in the sen sory evoked potencial,aud itory evoked potencial and pattern visual evoked potencial among four groups.Conclusion The results suggest that PAHs have no effect on the sensory veoked potencial,auditory evoked potencial and pattern visual evoked potencial in coke oven workers.