真菌性角膜溃疡临床特征分析

目的 总结真菌性角膜溃疡临床表现及其转归的临床规律。方法 回顾性分析近3年来的174例真菌性角膜溃疡病例，依据其转归分为穿孔组及未穿孔组，比较两组预后、病程、溃疡面积、前房积脓、眼压及菌种等方面的差异。结果 穿孔组及未穿孔组在预后、预后因素上的差异有显著性(P＜0．01)，穿孔组预后明显较未穿孔组差。溃疡面积、前房积脓、基质脓疡、高眼压、特殊菌种等为引起穿孔的高危因素。结论 真菌性角膜溃疡的危害性极大，往往可导致角膜穿孔且预后不良，应早期诊断并及时治疗。

Clinical investigation of mycotic corneal ulcer

Objective To summarize the law of the disease outcome and its prognosis. Methods 174 eyes with mycotic corneal ulcer were divided into two groups according to presence or absence of perforation and their prognosis, course of illness, surface area of ulceration, hypopyon, intraocular pressure, microbial spectrum were compared. Results There were significant differences in the prognosis and prognotic factors (P<0.01), with poor prognosis in the perforated group . The surface area of ulceration, hypopyon, stroma abscess, high IOP and certain microbial species were the high risk factors of perforation. Conclusion Mycotic corneal ulcer is hazardous and can lead to perforation easily, which should be diagnosed and treated earlier.