| 胰岛素抵抗代谢综合征与冠状动脉病变的相关性研究 |
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| 引用本文： | 银剑斌,韦金儒,卓柳安,陈世忠,蒋芳勇,曹燕清,谢晓丹.胰岛素抵抗代谢综合征与冠状动脉病变的相关性研究[J].右江医学,2008,36(4):393-395. |
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| 作者姓名： | 银剑斌 韦金儒 卓柳安 陈世忠 蒋芳勇 曹燕清 谢晓丹 |
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| 作者单位： | 广西医科大学第五附属医院,柳州市人民医院心血管内科,广西柳州,545001 |
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| 摘 要： | 目的探讨胰岛素抵抗、代谢综合征各种危险因子与冠状动脉病变之间的关系。方法将159例经冠状动脉造影确诊和排除冠心病患者分为两组,其中观察组83例,对照组76例。检测两组患者的空腹血糖、空腹胰岛素、血脂等生化指标,记录体重指数、高血压和糖尿病等代谢综合征危险因子,分析胰岛素抵抗指数(HOMA-IR)、代谢综合征各种危险因子与冠脉狭窄指数的相关性。结果观察组HOMA-IR,甘油三脂、低密度脂蛋白水平显著高于对照组(P均<0.01);观察组高血压、糖尿病的发生率显著高于对照组(P<0.05或<0.01);相关分析显示HOMA-IR与甘油三脂、低密度脂蛋白和冠脉狭窄指数呈显著正相关(P均<0.05);多元Logistic回归分析显示冠心病的发病与HOMA-IR、甘油三脂、低密度脂蛋白、高血压和糖尿病等代谢综合征危险因子有相关性(P<0.05或<0.01)。结论胰岛素抵抗与冠状动脉病变程度呈密切正相关;胰岛素抵抗是冠心病独立危险因素之一。
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| 关 键 词： | 胰岛素抵抗 代谢综合征 冠心病 |
Correlation of insulin resistance and metabolic syndrome with coronary heart disease |
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| YIN Jianbin,WEI Jinyu,ZUO Liuan,CHEN Shizhong,JANG Fangyoug,CAO Yanqing,XIE Xiaodan.Correlation of insulin resistance and metabolic syndrome with coronary heart disease[J].Youjiang Medical Journal,2008,36(4):393-395. |
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| Authors: | YIN Jianbin WEI Jinyu ZUO Liuan CHEN Shizhong JANG Fangyoug CAO Yanqing XIE Xiaodan |
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| Institution: | YIN Jianbin,WEI Jinyu,ZUO Liuan,CHEN Shizhong,JANG Fangyoug,CAO Yanqing,XIE Xiaodan(Cardiovascular Department of Liuzhou People\'s Hospital,the Fifth Affiliated Hospital of Guang Xi Medical University,Liuzhou 545001 Guangxi) |
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| Abstract: | Objective To investigate the correlation of insulin resistance,metabolic syndrome and coronary heart disease.Methods 159 patients diagnosed by coronary angiographic(CAG)were enrolled into this research,83 in coronary heart disease(CHD) group and 76 in normal control group without coronary heart disease.The levels of fasting blood glucose,blood insulin and plasma lipids respectively and recorded BMI,hypertension,diabetes mellitus in both groups were detected.Analyzed the correlation of homeostasis model asse... |
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| Keywords: | insulin resistance metabolic syndrome coronary heart disease correlation |
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