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A case of polymyositis complicated with myasthenic crisis
Authors:Yoshito Yoshidome  Shinji Morimoto  Naoto Tamura  Shigeto Kobayashi  Hiroshi Tsuda  Hiroshi Hashimoto  Yoshinari Takasaki
Affiliation:(1) Department of Internal Medicine and Rheumatology, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku Tokyo, 113-8421, Japan;(2) Department of Neurology and Geriatrics, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima 890-8520, Japan
Abstract:We report a 62-year-old woman who suffered from polymyositis (PM) complicated with myasthenic crisis. Electromyography and muscle biopsy indicated a diagnosis of PM; however, respiratory failure due to respiratory muscle weakness was seen in spite of a normal serum creatine kinase (CK) level. The positive anti-acetylcholine receptor antibody led us to the diagnosis of myasthenic crisis. PM with respiratory muscle weakness is rare. We suggest that the possibility of other neurological disorder complications should be considered when PM patients have respiratory muscle weakness out of proportion to the serum CK level.
Keywords:Anti-acetylcholine receptor antibody  Myasthenic crisis  Polymyositis
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