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蒲公英多糖的提取及降糖作用的研究
引用本文:侯丽然,孙丽娜,侯巍,滕杨,高金波.蒲公英多糖的提取及降糖作用的研究[J].黑龙江医药科学,2010,33(6):36-37.
作者姓名:侯丽然  孙丽娜  侯巍  滕杨  高金波
作者单位:佳木斯大学化学与药学院,黑龙江佳木斯154007
摘    要:目的:探讨提取蒲公英多糖的提取最佳工艺和蒲公英多糖对四氧嘧啶(Alloxan)糖尿病小鼠的降糖作用。方法:采用酶提取法、超声波提取法和超声波协同酶提取法,利用正交试验,优化各种提取方法的试验条件;用四氧嘧啶小鼠进行糖尿病模型的建立,用降糖仪测定小鼠的血糖,考察其降糖效果。结果:酶提取法的提取率为:9.203%;超声提取的提取率为:13.98%;超声协同酶法的提取率为:15.83%。结论:提取的蒲公英多糖均有降低血糖的作用(P〈0.01)。

关 键 词:蒲公英多糖  提取  降糖作用

Extraction and hypoglycemic function of Dandelion Polysaccharide
HOU Li-ran,SUN Li-na,HOU Wei,TENG Yang,GAO Jin-bo.Extraction and hypoglycemic function of Dandelion Polysaccharide[J].Heilongjiang Medicine and Pharmacy,2010,33(6):36-37.
Authors:HOU Li-ran  SUN Li-na  HOU Wei  TENG Yang  GAO Jin-bo
Institution:(College of Chemistry and Pharmacy of Jiamusi University,Jiamusi 154007,China)
Abstract:Objective: To investigate the optimum technological conditions of Dandelion Polysaccharide and the hypoglycemic effect of its extract in diabetic mice.Methods:Dandelion Polysaccharide was extracted by the methods of enzyme extraction,ultrasonic extraction and ultrasonic-enzyme synergistic extraction.The orthogonal test was used,and the experimental conditions were optimized.The hypoglycemic effect of Dandelion Polysaccharide was investigated by detecting the blood glucose.Results:The extraction rate of enzymes extraction was 9.203%.The extraction rate of ultrasonic extraction was 13.98%.The extraction rate of ultrasonic extraction with enzyme was 15.83%.Conclusion:Dandelion Polysaccharide extracted by all the three methods has hypoglycemic action and Dandelion Polysaccharide extracted by ultrasonic extraction shows the most remarkable hypoglycemic effect.
Keywords:Dandelion polysaccharide  extraction  hypoglycemic function
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