Study of erythrocytes by atomic force microscopy]

Working principle of Nanotop-202 atomic force microscope is described. The morphology of peripheral blood erythrocytes is studied under this microscope. A method for preparing the specimens is developed and the resultant cell images are described. The results demonstrate the potentialities of the method for morphometry, studies of fine structure of membrane surface, and manipulations with erythrocytes. Prospects of atomic force microscopy in hematological studies are discussed.