| HPLC法测定正天丸和正天胶囊中羟基红花黄色素A的含量 |
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| 引用本文： | 汪建君,李玲玲,陈惠玲,黄澜. HPLC法测定正天丸和正天胶囊中羟基红花黄色素A的含量[J]. 中国药品标准, 2013, 14(3): 197-200 |
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| 作者姓名： | 汪建君 李玲玲 陈惠玲 黄澜 |
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| 作者单位： | 汪建君 (厦门市药品检验所,厦门,361012)； 李玲玲 (厦门市药品检验所,厦门,361012)； 陈惠玲 (厦门市药品检验所,厦门,361012)； 黄澜 (厦门市药品检验所,厦门,361012)； |
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| 摘 要： | 目的:建立HPLC法测定正天丸和正天胶囊中羟基红花黄色素A的含量。方法:以十八烷基硅烷键合硅胶为填充剂,以甲醇-乙腈-0.7%磷酸溶液(26∶2∶72)为流动相,检测波长为403 nm。结果:羟基红花黄色素A在6.038 4～150.96μg·mL-1范围内呈良好的线性关系;平均回收率为100.0%,RSD=0.8%(n=6)。结论:本方法准确、快速、重现性好,可用于测定正天丸、正天胶囊中羟基红花黄色素A的含量。
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| 关 键 词： | 高效液相色谱法 正天丸 正天胶囊 羟基红花黄色素A |
| 收稿时间： | 2012-12-21 |
HPLC Determination of Hydroxysafflor Yellow A in Zhengtian Pills and Zhengtian Capsules |
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| Wang Jianjun,Li Lingling,Chen Huiling and Huang Lan. HPLC Determination of Hydroxysafflor Yellow A in Zhengtian Pills and Zhengtian Capsules[J]. , 2013, 14(3): 197-200 |
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| Authors: | Wang Jianjun Li Lingling Chen Huiling Huang Lan |
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| Affiliation: | (Xiamen Institute for Drug Control,Xiamen 361012 ) |
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| Abstract: | Objective： To establish a rapid determination of hydroxysafflor yellow A in zhengtian pills and zhengtian capsules. Methods： Using otcadecylsilane bonded silica gel as the stationary phase and a mixture of methanol,acetonitrile and 0. 7% phosphate acid solu-tion （26： 2： 72） as the mobile phase, and the detection wavelength was 403nm. Results：The calibration curves were linear in the range of 6. 0384-150. 96μg·mL^-1 for hydroxysafflor yellow A. the average recovery rate was 100. 0% ,RSD =0. 8% （n =6）. Conclusion： The method is simple, accurate, rapid and reproducible, and it can be used to control the contents of zhengtian pills and zhengtian capsules. |
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| Keywords: | HPLC zhengtian pills zhengtian capsules hydroxysafflor yellow A |
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