中西医结合治疗椎-基底动脉供血不足临床观察

目的：观察盐酸倍他司汀注射液联合盐酸利多卡因注射液及葛根素注射液治疗椎-基底动脉供血不足的临床疗效。方法：将椎-基底动脉供血不足患者132例随机分为2组,治疗组68例予盐酸利多卡因注射液0.1 g加入盐酸倍他司汀注射液500 m L内静脉滴注,1次/d,共7天,葛根素注射液0.4 g加入生理盐水250 m L内静脉滴注,1次/d,共14天;对照组64例予敏使朗6 mg,3次/d,盐酸氟桂利嗪10 mg,1次/d,每晚口服,盐酸丁咯地尔0.2 g加入生理盐水250 m L内静脉滴注,1次/d,共14天。观察2组患者临床疗效及椎-基底动脉血液流速变化情况。结果：治疗组和对照组总有效率分别为92.65%、76.56%,治疗组总有效率优于对照组（P〈0.05）;治疗组椎-基底动脉血液流速改善优于对照组（P〈0.05）。结论：盐酸倍他司汀注射液与盐酸利多卡因注射液、葛根素注射液联合应用是椎-基底动脉供血不足患者的有效治疗方法。

Clinical Observation on Treating Vertebrobasilar Insufficiency by Integrative Medicine

Objective： To survey clinical effects of betahistine hydrochloride injection, lidocaine hydrochloride injection and puerarin injection in the treatment for vertebrobasilar insufficiency. Methods： All 132 cases were randomized into two groups, 68 cases of the treatment group accepted intravenous dripping of lidocaine hydrochloride injection, 0.1g, added into betahistine hydrochloride injection, 500 m L, once each day, for seven days, puerarin injection, 0.4 g, added into physiological saline, 250 m L, oncer per day, for 14 days; 64 cases of the control group received oral administration of betahistine, 6mg, three times each day, and flunarizine hydrochloride, 10 mg, once each day, in the evening, buflomedil hydrochloride, 0.2g, added into physiological saline, 250 m L, oncer per day, for 14 days. Curative effects of both groups and the changes of vertebrobasilar blood flow were observed. Results： Total effective rates of the treatment group and the control group were 92.65% and 76.56% respectively, the treatment group was superior to the control group obviously（P〈0.05）; the treatment group was better than the control group in improving vertebrobasilar blood flow. Conclusion： The combination of betahistine hydrochloride injection, lidocaine hydrochloride injection and puerarin injection are effective methods for the patients with vertebrobasilar insufficiency.