| 微电极靶点定位外科治疗帕金森病 |
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| 引用本文： | 庞琦,王成伟,徐广明,张珑,孙金龙,朱礼峰.微电极靶点定位外科治疗帕金森病[J].山东大学学报(医学版),2000,38(3):282-283. |
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| 作者姓名： | 庞琦 王成伟 徐广明 张珑 孙金龙 朱礼峰 |
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| 作者单位： | 1. 山东医科大学第二附属医院神经外科
2. Dept.of Neurosurgery,Aarhus University Hospital,Denmark |
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| 摘 要： | 目的探讨微电极记录技术在帕金森病外科治疗中的作用。方法采用微电极电生理记录技术监测术中靶点，对帕金森病31例进行手术治疗，其中苍白球毁损术14例、丘脑毁损术6例、深部脑电刺激术11例。结果最终毁损靶点较MR定位靶点位置更换率为80．6％，手术效果优良，有效率100％，原有症状术后改善率达87．1％，无永久并发症。结论微电极记录技术的应用能显著提高定位精度，减少并发症和提高手术效果。
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| 关 键 词： | 帕金森病 微电极记录 苍白球毁损术 丘脑毁损术 深部脑电刺激术 |
| 文章编号： | 1000-0496(2000)03-0282-02 |
| 修稿时间： | 2000年4月3日 |
MICROELECTRODE GUIDED SURGERY FOR PARKINSON'S DISEASE |
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| Gorm von Oettingen.MICROELECTRODE GUIDED SURGERY FOR PARKINSON''S DISEASE[J].Journal of Shandong University:Health Sciences,2000,38(3):282-283. |
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| Authors: | Gorm von Oettingen |
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| Abstract: | Objective:To discuss the role of microelectrode recording in surgical management of Parkinson's disease. Methods:Microelectrode recording was used as intraoperative tanget in 31 patients with Parkinson's disease.14 cases underwent pallidotomy,6 cases underwent thalamotomy and 11 cases underwent deep brain stimulation. Results:It was found that the final targets had been greatly changed from MR targets, the change rate was 80.6%.The outcome of operation was excellent,every patient showed improvement and were 87.1% of symptoms relieved.No patient developed permanent complications. Conclusion:Microelectrode recording could highly increase the precision of localization,decrease the rate of complications and produce a better outcome. |
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| Keywords: | Parkinson's disease Microelectrode recording Thalamotomy Pallidotomy Deep brain stimulation |
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