系统性红斑狼疮妊娠合并妊高征的前瞻性研究

目的：探讨系统性红斑狼疮（ＳＬＥ）对重度妊高征（ＰＩＨ）发病影响及对母儿危害。方法：８０例ＬＳＥ妊娠的临床资料前瞻性研究。结果：活动期ＳＬＥ肾炎孕妇合并重度ＰＩＨ的发生率１０／２２例（４５％）。稳定期ＳＬＥ肾为１／１２例（８．３％），其它皮肤型ＳＬＥ２／４６例（４．３％）。文献报告活动期ＳＬＥ肾炎与重度ＰＩＨ很喟 母死亡率可提高５０－８０％，胎儿死亡率１２．９－４５．５％。结论：两者诊断正确时，分

The Prospective study of SLE with pregnancy induced hypertension

Objective: To study the morbility influence, impairment of maternal fetal of SLE to severe PIH. Meth-ods:Prospective analysis of clinical materials of 80 cases systemic lupus erythematous accompained with pregnancy in-duced hypertension. Results:Activity SLE with nephritis in pregnancy complicated with severe PIH. The morbidity ratewere 10/22 cases (45% ). Stabled SLE nephritis 1/12 cases (8. 3% ). Other skin typed SLE 2/46 cases (4. 3% ). Ac-cording to references report[1],Activity SLB with nephritis is difficult to differentiate from severe PIH and maternal mor-tality rate up to 50~80%. Fetal mortality rate reads as 12. 9~ 45. 5 %[1.5]. Diagnosis proper of maternal fetal each in-creaseded steroids administration to control the activity and magnesium sulfate to control the symptom of disease. Intraaminotic injection of dexamethasone to interfere prematurity can save the mother from risk to safety and increase the su-ruival rate of prematurity fetal. We reported on the survived 80 cases of mother and 81 cases of new born fetal (involved1 case of twin).