Nitazoxanide compared with quinfamide and mebendazole in the treatment of helminthic infections and intestinal protozoa in children |
| |
Authors: | Davila-Gutierrez Cesar E Vasquez Clemente Trujillo-Hernandez Benjamin Huerta Miguel |
| |
Affiliation: | Unidad de Investigación en Epidemiología Clínica, Hospital General de Zona y Medicina Familiar No. Uno, Dr. Leonel Ramírez García, Instituto Mexicano del Seguro Social, Colima, México. |
| |
Abstract: | The present study was carried out to evaluate the effectiveness of nitazoxanide compared with that of quinfamide, mebendazole, or both in the treatment of intestinal protozoa and helminthic infections. A total of 677 stool specimens from children aged 2-12 years living in 3 communities of Colima, México, were analyzed in order to detect the presence of cysts, trophozoites, eggs, or larvae of intestinal protozoa or helminths. A total of 275 infected children were enlisted in a double-blind controlled study and randomly assigned to one of 2 treatment groups: Group A, nitazoxanide (200 mg for 3 days) and Group B, quinfamide (100 mg for 1 day), mebendazole (200 mg for 3 days), or both. A posttreatment fecal examination was conducted on Day 14 from treatment initiation. In Group A (n = 143), the parasitosis eradication rate was superior to that of Group B (n = 132). However, there was no significant difference between the 2 groups (P > 0.05). |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|