前哨淋巴结活检在早期乳腺癌患者腋窝管理中的研究进展

传统的观点认为腋窝淋巴结清扫(axillary lymph node dissection,ALND)是前哨淋巴结(sentinellymph node,SLN)阳性乳腺癌患者的标准治疗方法,而ALND容易引起上肢水肿、功能障碍等术后并发症,影响患者生活质量.近几年研究显示,对于SLN阳性的早期乳腺癌,并非所有患者都需...

Research progress of sentinel lymph node biopsy in axillary management for early breast cancer patients

Traditionally,axillary lymph node dissection(ALND)is the standard treatment for patients with sentinel lymph node-positive breast cancer,while ALND tends to cause upper limb edema,dysfunction and other postoperative complications,which affect the quality of life of patients.Studies in recent years have shown that not all patients need ALND for SLN-positive early breast cancer.For early breast cancers patients who with micrometastasis and 1-2 SLN-positive,omitting ALND dose not affect overall survival.For breast cancer patients with positive clinical axillary lymph nodes,after the clinical axillary lymph nodes turn to the negative through neoadjuvant chemotherapy,whether SLNB can accurately assess the status of axillary lymph nodes is still controversial.This article will summarize the latest literature on breast cancer axillary treatment,and the therapeutic strategies for early breast cancer patients with positive sentinel lymph nodes and the clinical feasibility of SLNB after neoadjuvant chemotherapy for clinical lymph node positive breast cancer are reviewed.