SARS-CoV-2 Infection Hospitalization Rate and Infection Fatality Rate Among the Non-Congregate Population in Connecticut |
| |
| Authors: | Shiwani Mahajan César Caraballo Shu-Xia Li Yike Dong Lian Chen Sara K Huston Rajesh Srinivasan Carrie A Redlich Albert I Ko Jeremy S Faust Howard P Forman Harlan M Krumholz |
| |
| Institution: | 1. Center for Outcomes Research and Evaluation, Yale New Haven Hospital, Conn;2. Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Conn;3. The Gallup Organization, Washington, DC;4. Yale Occupational and Environmental Medicine Program, Department of Internal Medicine, Yale School of Medicine, New Haven, Conn;5. Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, Conn;6. Division of Health Policy and Public Policy, Department of Emergency Medicine, Brigham and Women''s Hospital, Harvard Medical School, Boston, Mass;7. Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Conn;8. Department of Health Policy and Management, Yale School of Public Health, New Haven, Conn |
| |
| Abstract: | BackgroundInfection fatality rate and infection hospitalization rate, defined as the proportion of deaths and hospitalizations, respectively, of the total infected individuals, can estimate the actual toll of coronavirus disease 2019 (COVID-19) on a community, as the denominator is ideally based on a representative sample of a population, which captures the full spectrum of illness, including asymptomatic and untested individuals.ObjectiveTo determine the COVID-19 infection hospitalization rate and infection fatality rate among the non-congregate population in Connecticut between March 1 and June 1, 2020.MethodsThe infection hospitalization rate and infection fatality rate were calculated for adults residing in non-congregate settings in Connecticut prior to June 2020. Individuals with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies were estimated using the seroprevalence estimates from the recently conducted Post-Infection Prevalence study. Information on total hospitalizations and deaths was obtained from the Connecticut Hospital Association and the Connecticut Department of Public Health, respectively.ResultsPrior to June 1, 2020, nearly 113,515 (90% confidence interval CI] 56,758-170,273) individuals were estimated to have SARS-CoV-2 antibodies, and there were 7792 hospitalizations and 1079 deaths among the non-congregate population. The overall COVID-19 infection hospitalization rate and infection fatality rate were estimated to be 6.86% (90% CI, 4.58%-13.72%) and 0.95% (90% CI, 0.63%-1.90%), respectively, and there was variation in these rate estimates across subgroups; older people, men, non-Hispanic Black people, and those belonging to 2 of the counties had a higher burden of adverse outcomes, although the differences between most subgroups were not statistically significant.ConclusionsUsing representative seroprevalence estimates, the overall COVID-19 infection hospitalization rate and infection fatality rate were estimated to be 6.86% and 0.95%, respectively, among community residents in Connecticut. |
| |
| Keywords: | COVID-19 Infection fatality rate Infection hospitalization rate SARS-CoV-2 Seroprevalence |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
