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Arterio-embolic ischemic stroke in children with moyamoya disease |
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| Authors: | Peter Horn Eva Bueltmann Christoph V. Buch Peter Schmiedek |
| Affiliation: | (1) Department of Neurosurgery, Universitätsklinikum Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1–3, 68167 Mannheim, Germany;(2) Department of Neuroradiology, Universitätsklinikum Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1–3, 68167 Mannheim, Germany;(3) Department of Pediatrics, Universitätsklinikum Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1–3, 68167 Mannheim, Germany |
| Abstract: | Introduction Moyamoya (MM) disease is a rare steno-occlusive cerebrovascular disease known to occur in children and adults. The most serious complications in children are developmental delay and mental retardation due to recurrent hemodynamic stroke. Cases We report two pediatric patients without coagulopathy who suffered from severe arterio-embolic ischemic complications despite antiplatelet medication. Discussion These observations underline the potential impact of cerebral thromboembolism on the pathophysiology of the stroke and thus on the treatment of children with MM disease. |
| Keywords: | Moyamoya Ischemic stroke Hemodynamic compromise Vasculopathy Thromboembolism |
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