| 外阴营养不良中fas/apol-1表达的生物学意义 |
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| 引用本文： | 杨树君,陈铭,陈诵芬,尹格平,孙晓明.外阴营养不良中fas/apol-1表达的生物学意义[J].中国实验诊断学,2000,4(3):111-112. |
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| 作者姓名： | 杨树君 陈铭 陈诵芬 尹格平 孙晓明 |
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| 作者单位： | 济南军区总医院,妇产科,山东,济南,250031 |
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| 摘 要： | 探讨外阴营养不良组织中ｆａｓ／ａｐｏｌ－１（ＣＤ９５）表达与其发病机理的关系。方法采用流式细胞仪检测４２例外阴营养不良新鲜组织中ｆａｓ／ａｐｏｌ－１的表达，并取１０一正常正外阴组织作对照。结果硬化性苔鲜组织中ｆａｓ／ａｐｏｌ－１的表达高于对照组及鳞状细胞增生混合性营养不良组织中的表达。结论ｆａｓ／ａｐｏｌ－１诱导的凋亡与外阴营养不良有密切的关系。
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| 关 键 词： | 外阴营养不良 流式细胞仪 fas／apol－1 细胞凋亡 |
| 文章编号： | 1007-4287(2000)03-0111-02 |
| 修稿时间： | 1999年12月22 |
The biological significace of expression of fas/apol-1 in vulvar dystrophy |
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| YANG Shu-jun, CHEN Ming, CHEN Song-fen,et al.The biological significace of expression of fas/apol-1 in vulvar dystrophy[J].Chinese Journal of Laboratory Diagnosis,2000,4(3):111-112. |
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| Authors: | YANG Shu-jun CHEN Ming CHEN Song-fen |
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| Abstract: | Objectire To study the relation between expression of fas/apol-1 in vulvar dystrohy and mechanism of vulvar dystrophy. Methods Flow cytometry was used to determine the expression of fas/apol-1 fresh yulvar dystrophy samples in 42 cases and lonormal fresh vulvar samples were taken as the controls. Results Expression of fas lichen sclerosus was singnificanly higher than that in squamous cell hyperplasia and the control (P<0.01). There was no statistical singnificance between the squamous cell hyperplasia and the mixture. Conclusion There was close association between apoptoss indused by fas/apol-1 and themechanism of vulvar dystrophy. |
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| Keywords: | Apoptosis Vulvar dystrophy Flow cytometry |
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