孕早期妇女血清学指标异常与妊娠不良结局的相关性分析

目的分析孕早期妇女血清学指标(血清PAPP-A水平等)异常与妊娠不良结局的相关性。方法回顾性分析我院妇产科2010年7月至2012年7月收治的180例孕周在13周以内的孕妇的临床资料。结果 2组孕妇血清中的freeβ-HCG(游离人绒毛促性腺激素)和PAPP-A(血浆蛋白A)水平的MOM值中,和对照组相比,观察组患者明显偏低,二者差异具有统计学意义(P<0.05)。结论孕早期妇女血清中的freeβ-HCG和PAPP-A水平异常极易导致胎儿畸形、胚停、自发性流产等不良妊娠结局,因此我们在临床上应该格外留意。

The Correlation of Serum Markers and the Abnormalities and Poor Pregnancy Outcomes of Women in Early Pregnancy

Objective To analyze the correlation of serum markers （serum PAPP-A levels, etc.） and the abnormalities and poor pregnancy outcomes of women in early pregnancy. Methods Retrospectively analyzed the clinical data of the 180 cases of pregnant woman whose maternity gestational age was less than 13 weeks and had been admitted to our hospital from July 2010 to July 2012. Results The MOM values of the free[3-HCG （free human chorionic gonadotropin） and PAPP-A （plasma protein A） levels in the maternal serum, compared to the control group, the observation group patients＇ were significantly lower, the difference was statistically significant （P 〈0.05）. Conclusions If the early pregnancy women＇s serum free[3-HCG and PAPP-A levels are abnorm^-1, then it can cause spontaneous abortion, such as fetal malformations, embryo stopped, adverse pregnancy outcomes and so on, it is worth the extra attention in the clinical.