武汉市气传真菌与吸入性变态反应疾病关系回顾分析

目的：调查武汉经济技术开发区气传真菌的种类、数量及飘散规律,探讨其与吸入性变态反应疾病的关系。方法：2007年2月～2008年1月,用空气曝片法,每日曝片1张,对气传真菌进行调查。同时选择2007年武汉经济技术开发区神龙医院257例支气管哮喘、过敏性鼻炎患者进行发病季节调查,并分析其与真菌浓度间的相关性。结果：全年共观察到真菌种类20多种,收集到真菌孢子4841个。气传真菌飘散高峰在4～10月份。开发区气传真菌的高峰期与吸入性变态反应疾病发病季节基本相吻合。结论：调查结果对开发区吸入性变态反应疾病的流行病学研究和临床治疗、预防提供了重要依据。与空气中真菌的种类及数量基本一致,提示临床上需要加以关注与研究针对性早期干预措施。通过调查分析初步明确了武汉经济技术开发区气传真菌的种类、数量和分布规律,为本地区真菌相关的吸入性变态反应性疾病的临床诊断、预防、治疗提供重要依据。

Review of the association between airborne fungus and inspiratory allergosis

Objective：To investigate the variety of the air-borne fungus in Wuhan economic reform zone,and study the associations between airborne fungus and allergic disease.Methods：From February 2007 to January 2008,we used exposed-glass-in-air method to investigate quantity of the fungus.Meanwhile,257 patients,who suffered from bronchial asthma and allergic rhintics,were chosen to participate in the research.These 257 patients were diagnosed the bronchial asthma and allergic rhintics in Shenlong Hospital in Wuhan Economics and Tech Development District during the year of 2007.We analyzed the nosogenic season and found out the correlations between incidence rate of bronchial asthma and allergic rhintics and concentration of the fungus.Results：We observed more than 20 sorts of fungus,including 4 841 fungal spores,in the whole year.Spring and summer were two seasons that had higher numbers of divergence.The numbers of di vergence decrease in fall and winter.The fastiginm of airborne fungus tallies with nosogenic season of inspiratory allergosis.Conclusion：The results provide clinical evidence to future treatment and prevention of inspiratory allergosis and other epidemic diseases.