Effets de lésions du septum,de l'amygdale,du striatum,de la substantia nigra et de l'ablation des bulbes olfactifs sur le comportement d'agressivité intraspécifique induit par l'apomorphine chez le rat

Lesions of the septal region have been found to enhance apomorphine-induced aggressive behavior, without however facilitating its appearance in non-aggressive rats. This effect has been observed following bulbectomy or destruction of the anterior part of the striatum. Conversely, lesions of the amygdala or substantia nigra have been shown to produce an inhibitory effect on this behavior. It has also been observed that the septal syndrome was the most clear-cut one in those rats which were the most sensitive to the aggresion inducing effect of apomorphine. These results have been compared with those related to other aggressive behaviors, and the site of action of apomorphine has been discussed.

L'auteur remercie vivement le Docteur J. Jacob pour les précieux conseils qu'il lui a apporté au cours de ce travail et de la rédaction de ce manuscrit. Il remercie également le Professeur D. Albe-Fessard pour son aimable acceuil à l'Institut Marey et le Docteur J. Delacour qui l'a si obligeamment initié aux techniques stéréotaxiques.