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The charged linker of the molecular chaperone Hsp90 modulates domain contacts and biological function
Authors:Markus Jahn  Alexandra Rehn  Benjamin Pelz  Bj?rn Hellenkamp  Klaus Richter  Matthias Rief  Johannes Buchner  Thorsten Hugel
Affiliation:aPhysik-Department E22 and;bDepartment Chemie, Technische Universität München, 85748 Munich, Germany; and;cMunich Center for Integrated Protein Science, 85748 Garching, Germany
Abstract:
Keywords:single molecule   optical tweezers   Hsp90 conformation   FRET   asymmetric state
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