腰硬联合加氯胺酮麻醉在小儿手术中的应用

目的：观察氯胺酮辅助腰- 硬联合麻醉用于小儿手术的临床疗效.方法：选择择期手术患儿93 例,随机分为观察组50 例（腰-硬联合加氯胺酮麻醉组） 和对照组43 例（氯胺酮静脉复合麻醉）.观察两组患儿麻醉前后平均动脉压（MAP）、心率（HR）、脉搏氧饱和度（SpO2）的变化及氯胺酮药物剂量、术后清醒时间及不良反应的发生情况.结果：两组MAP、HR、SpO2 比较差异无统计学意义,观察组氯胺酮用药剂量、术后清醒时间明显低于对照组（P〈0.05）,不良反应发生率为18.0%（9/50）,与对照组比较差异有统计学意义（P〈0.01）.结论：腰硬联合加氯胺酮麻醉用于小儿手术效果满意,安全性高,是小儿手术的理想麻醉方法.

The Clinical Application of Ketamine Combined with Spinal-epidural Anesthesia Used for Pediatric Operation

Objective ：To observe the clinical effects of Ketamine aided combined spinal-epidural anesthesia in pediatric operations. Method ：93 pediatric surgery were randomly allocated to observation group（Ketamine aided Combined spinal-epidural anesthesia, n=50） and control group（Ketamine intravenous combined anesthesia, n=43）.The variation of MAP, HR, SpO2 and the total dosage of ketamine, the wake time, the adverse reactions were observed.Result ：There were no significant difference of MAP, HR, SpO2 between two groups.The total dosage of ketamine and the postoperative awake time in observation group were remarkably lower than those in control group（P〈0.05）, the adverse reactions incidence was 18.0%（9/50）, those were significantly lower than control group.Conclusion ：Ketamine aided Combined spinal-epidural anesthesia was safe, the effect of anesthetic was better, it was the ideal anesthetic for pediatric surgery.