深圳市南山区2005年流感监测结果初步分析

目的探讨深圳市南山区2005年流感流行规律，为有效防制提供依据。方法通过流行病学、血清学和病原学监测，对深圳市南山区流感流行情况进行分析。结果2005年流感样病人数在全年各月有明显变化，4月、5月、9月份流感病人相对较多，10月份流感病人相对较少；0-岁组、5-岁组流感样病人明显较多，分别占总流感样病人数的43．4％、25．0％；2005年共分离到毒株56株，分离率为12．0％，其中H3N2亚型44株，占78．6％，H1N1亚型6株，占10．7％，B型毒株6株，占10．7％，其中5株B型毒株为9月分离。人群中A型、B型流感抗体的阳性率分别为92．9％、70．9％。结论2005年深圳市南山区流感疫情相对较为平静，H3N2型毒株为流感流行的优势毒株，B型流感病毒的流行有增强的趋势，监测结果显示流感病毒优势毒株如不发生大的变异，与目前深圳市使用的疫苗株型别基本相同，则近期不会发生流感较大规模的流行。

Preliminary analysis of results in monitoring of influenza in Nanshan District of Shenzhen City in 2005

Objective To explore the prevalent characteristics of influenza in Nanshan District of Shenzhen City in 2005. Methods Epidemiological, pathogenic and serologic methods were applied to analyze the prevalence of influenza in Nanshan Ddistrict of Shenzhen City. Results The number of flu-like cases were different in each month of whole year. Most of the cases occurred in April, May and December. The number of cases increased slightly in zero-year age group and five-year age group accounted for 43.4% and 25.0% of the total cases. There 56 strains of influenza viruses were isolated from samples in this period, with an isolation rate of 12.0%. Of the 56 strains, 44 were identified as subtype H_3N_2 ( 78.6%), 6 strains subtype as H_1N_1,( 10.7%), 6 strains as B (10.7%). 5 strains were isolated in September. The sero-positive rates of antibody to influenza A, influenza B in the general population were 92.9% and 70.9%. Conclusion H_3N_2 is the dominant prevalent strain. There are not much differences between dominant strain and vaccine strain. Large scale outbreak of influenza would not occur recently.