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老年冠心病患者外周血血友病因子和内皮细胞的检测及其相关性分析
引用本文:王双,王雷,夏朝华,唐发清. 老年冠心病患者外周血血友病因子和内皮细胞的检测及其相关性分析[J]. 湖南师范大学学报(医学版), 2008, 5(1)
作者姓名:王双  王雷  夏朝华  唐发清
作者单位:1. 中南大学湘雅医院检验科,湖南,长沙,410008
2. 中南大学湘雅医院眼科,湖南,长沙,410008
摘    要:目的:探讨老年冠心病(CAD)患者血管内皮细胞受损与血友病因子(vWF)的关系。方法:选择27例老年CAD患者和24例正常老年人(NC组),测定其循环内皮细胞(CEC)数、血浆血管性血友病因子(vWF)的水平。结果:老年CAD患者CEC(9.30±4.11)和血浆vWF含量(196.16±32.34)明显高于NC组(2.52±0.91,117.77±18.99,P<0.01);且CEC数量与vWF水平呈正相关(r=0.823,P=0.0001)。结论:老年CAD患者血管内皮的损伤与vWF相关。

关 键 词:冠心病  循环内皮细胞  血管性血友病因子

Plasma vWF and Circulating Endothelial Cells were Detected in Elderly Patients with Coronary Artery Diseasea and Relationship Analysis
WANG Shuang,WANG Lei,XIA Chao-hua,TANG Fa-qing. Plasma vWF and Circulating Endothelial Cells were Detected in Elderly Patients with Coronary Artery Diseasea and Relationship Analysis[J]. Journal of Hunan Normal University(Medical Science), 2008, 5(1)
Authors:WANG Shuang  WANG Lei  XIA Chao-hua  TANG Fa-qing
Affiliation:WANG Shuang1,WANG Lei1,XIA Chao-hua2,TANG Fa-qing1
Abstract:Objective Probe the relationship between circulating endothelial cells and piasma in elderly coronary artery disease(CAD) patients.Methods 27 patients with CAD and 24 elderly healthy population were selected as subjects,and their circulating endothelial cells count and plasma vWF were detected.Results Circulating endothelial cells count and plasma vWF level were higher in CAD patients than its of control group(9.30±4.11 vs.2.52±0.91,P<0.01) and(196.16±32.34 vs.117.77±18.99,P<0.01).Plasma vWF level had posit...
Keywords:coronary artery disease  circulating endothelial cells  von Willebrand Factor(vWF)
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