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Complement-fixing platelet autoantibodies in autoimmune thrombocytopenia
Authors:W. Kayser  C. Mueller-Eckhardt  U. Budde  R. E. Schmidt
Abstract:A 16-year-old male patient is described with chronic autoimmune thrombo-cytopenic purpura and, after two years, “warm” autoimmune hemolytic anemia (Evans syndrome) who transiently developed complement-fixing platelet autoantibodies. The autoreactivity of these antibodies was established by quantitative complement fixation as well as by absorption and elution studies using autologous platelets. We believe this to be the first documented case with this very rare and peculiar type of platelet autoantibody.
Keywords:platelet autoantibodies  complement fixation  autoimmune thrombocytopenia
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